Many organs are depleted to have illness coming on the mechanism is announced after burning

Many organs are depleted to have illness coming on the mechanism is announced after burning
Many organs are depleted to have illness coming on the mechanism is announced after burning
It is reported " The high moving rate clan albumen B1 can promote peripheral blood and immune organ regulating T cell (Treg) after burning seriously Immunity last function ripe,it is secrete by inhibiting cell factor in a large amount not to and not stimulate by it, cause organism cell immunological function disorderly, cause patient play an important role in the pathologic course of death finally and in depleted many organ of bringing out" . Seminar which the first affiliated hospital Professor Yao YongMing of general hospital of PLA led, and can burn a patient seriously prospectively to work out this important achievement through a series of animal's experiment, this achievement was published on " the critical disease was guarded " and " shock " magazine a few days ago. Vice editor-in-chief Lowry professor of magazine of " shock " thinks, this research has offered the new concept for burning and treating, and is regarded as the key introduction of the main innovative light spot. The research in recent years verifies, inflammation and immunoreactive disorder are not merely shown as " excessive inflammation reacts " in many organs of due to pyemiapyaemia are depleted ,Still appear at the same time " The immunological function is inhibited " State. And Treg is mainly giving play to the immune inhibition effect to cell in the complicated immune adjustment network of pyemiapyaemia as one of the important regulation cells of the immune system. Yao YongMing thinks, canvasses function and regulation mechanism of Treg in burning pyemiapyaemia thoroughly in view of the above, will contribute to predicting the developing direction of inflammation, will announce the depleted pathologic course of many organs after burning seriously. Researcher's animal's model of recovering of the delay through scalding, observe and scald the impact on Treg surface molecule and immunological function seriously. On this basis, burn the patient above the 30% of whole area to pay and observe 106 dynamically. The result reveals, compared with normal control group, burn a patient seriously differently and burn the area group and every time point after wounded, Treg surface molecule expresses and obviously increases. Measure Treg, secrete, lie between plain - 10 ability in vain further, result indicate this kind resist inflammation cell factor, demonstrate the variation tendency the same as surface molecule. Animal's experiment and clinical case materials all prove, erupting pyemiapyaemia simultaneously causes many organs to be depleted and is closely related with after Treg surface molecule and inhibition cell factor and burning patients wounded seriously of secretion, and may play an important role in the depleted patient's prognosis of many organs is bad. (Zhang Xian cherishes)


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