Australian scientist: Determine human body's key albumen of immune memory

Australian scientist: Determine human body's key albumen of immune memory
Australian scientist: Determine human body's key albumen of immune memory
Medical scientist of research institute Australian Walter - Eliza and Hall is a recent new discovery, will change the views on memory ability operation mechanism of immune system of the body for a long time of people. The result of study is published in Science. Memory B cells play an essential role in the memory for a long time as one kind of immune cells. " for validity of all vaccine that is using of the present stage, the production of B cells and the corresponding antibody is a key step " ,DavidTarlinton participating in being studied shows, " further study and know the molecule interaction principle in the immune course clearly, it is very important " . In this experiment, Tarlinton and its colleague IngelaVikstrom doctor are known as " urging to survive " to one kind The albumen carries on research, this kind of albumen can control the surviving of memory B cells. Dr. Vikstrom says, the memory of B cells is known as " growing in the centre " in one kind Temporary for cell structure take shape,kinds of cell structure can reply activity against immune system. Scientist use heredity and the intersection of pharmacology and means urge, survive to two know already albumen Bcl-xL and Mcl-1 go on research, find Mcl-1 albumen is influencing formulation and maintenance of B cell memory to a great extent in surprise, and this and Bcl-xL which scientists generally think influence key views of the albumen of memory B cells to be totally different. Mcl-1 albumen is a kind of important surviving albumen for cancer cell. This discovery may let people produce the new knowledge to the treatment of cancer, at the same time, too inhibit research to transplant rejection exert an influence to one's own the intersection of immunity and disease treatment discovery this. Relevant instrument: GS-800 regulating mere density scanner LSRII flowing cell appearance Finish people: Defend seminar once of Tallin big Laboratory: Australian Walter - Eliza and Hall medical medical pathological research institute of biological centre molecule of Vienna of Austria of department of biology of Melbourne university of research institute


|