Streptococcus study develop change treat and cure principle

Streptococcus study, develop, change, treat and cure principle
Streptococcus study, develop, change, treat and cure principle
It is reported ' The intersection of reporter and Zheng dexterous) The scientist of our country adopts and evolves the analytical method of the relation, has proposed new difference law of the streptococcus - -Divide the streptococcus into medium-sized pathogenic group, high pathogenic group and popular group, and proposed people and infected pathogenic mechanism hypothesis of two stages of the streptococcus. According to two stage hypothesises, high pathogenic or epidemic streptococcuses such as the 1 type, 7 type streptococcus array,etc. infect treating the principle in early days and should take place and resist the shock treatment in order to prevent shock of the patient, but not only the antibacterial treatment that usually thinks. Research report this issue infectious disease learn at the " infectious disease magazine " in U.S.A. a few days ago. This journal editorial office was allotted and commented on and claimed, the discovery of the Chinese scientist has offered the new visual field for that the streptococcus infected epidemiology. In 2005, Sichuan Province of our country broke out the largest scale people were infected with the streptococcus epidemic situation in the world. 61 people present, poison kinds of the intersection of shock and symptom in 215 patient, 38 people die, only about 24 hours on average from patient to death. The streptococcus has been initiated and poisoned one kind of shock phenomena and aroused great concern from international academia with all sorts of conjectures. What happened on earth in the pathogen in the middle of this? By China CDC ' Center for Disease Prevention and Control) Prevent and cotrol this research that chief researcher Xu JianGuo heads the list of signers and launches in infectious disease, find out the streptococcus which initiates the epidemic situation of Sichuan of 2005 in order that after 2 type serum, 7 type array with strong virulence and pathogenic strength, further found in serum of shock patient that Sichuan streptococcus was caused in 2005, there is the factor density of 6 kinds of cells that unusually rises, thus lead to the fact patient's many organs have depleted function, even die. Analyzed and finds through the genome, the streptococcus evolves to high pathogenic group of course from medium-sized pathogenic group, have obtained 136 pieces of genome island, include 5 pieces of virulence island; Evolve to popular group of course from high pathogenic group, has obtained 5 pieces of genome island. Xu JianGuo,etc. has also proposed " The course of disease of two stages " Hypothesis. From high to cause a disease group or prevailing group of streptococcuses enters the organism first stage, generally in about 24 hours. Pathogens are bred in the blood, interact with the constellation chief cell, stimulate the organism to produce a large number of cell factors during that time, lead to the fact that is poisoned a kind of shock syndrome and the death takes places the streptococcus. If the host can spend the first stage, then the streptococcus will demonstrate the pathogenic mode that we realized in the past, reach all internal organs with blood flow ' For instance liver, spleen, heart,etc.) , the joint, symptoms such as membrane inflammation and arthritis,etc. in the heart appear. At the second stage, the streptococcus will also break through the blood brain protective screen, invade the central nervous system, meninx inflammation appears. Xu JianGuo says, according to this hypothesis, only takes measures as soon as possible, prevent shock, can reduce the streptococcus and infect the case fatality rate effectively.


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